Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NAAA | Q02083 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093913 | 1.00 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9068157 | 1.00 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9093917 | 1.00 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL2050162 | 1.00 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| Hydrochloric Acid SCHEMBL7276411 | 0.98 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL1547678 | 0.98 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL1547680 | 0.98 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| Hydrochloric Acid SCHEMBL7274667 | 0.97 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9094626 | 0.93 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2LMNANAAA | |
| SCHEMBL9094616 | 0.93 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2LMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8936922-B2 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | CHEMSMART, LLC (US) | 2015-01-20 | — | — | US | claimed |
| US-20120289725-A1 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | CHEMIC LABORATORIES, LLC | 2012-11-15 | — | — | US | claimed |
| US-20110136188-A1 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | CHEMSMART, LLC | 2011-06-09 | — | — | US | claimed |
| US-7863025-B2 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | CHEMIC LABORATORIES, INC. (US) | 2011-01-04 | — | — | US | claimed |
| EP-1802763-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | Chemic Laboratories, Inc (US) | 2007-07-04 | — | — | EP | claimed |
| US-20070082039-A1 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids, the use of the same as percutaneous permeation enhancers, and topical gels for the transdermal delivery of steroids | CHEMSMART, LLC | 2007-04-12 | — | — | US | claimed |
| WO-2007038496-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF HYDROXY CARBOXYLIC ACIDS, THE USE OF THE SAME AS PERCUTANEOUS PERMEATION ENHANCERS | CHEMIC LABORATORIES, INC. (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2006044926-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF α-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | CHEMIC LABORATORIES, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060084154-A1 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | CHEMIC LABORATORIES, LLC | 2006-04-20 | — | — | US | claimed |
| US-20250064713-A1 | COSMETIC COMPOSITIONS | ELEBLEND LLC (US) | 2025-02-27 | — | — | US | disclosed |
| US-20240351957-A1 | ADMIXTURE TO CONTROL THE HEAT FLOW FROM MINERAL BINDER COMPOSITIONS, MINERAL BINDER COMPOSITIONS, AND PRODUCTION METHOD THEREOF | SIKA TECHNOLOGY AG (CH) | 2024-10-24 | — | — | US | disclosed |
| WO-2024175610-A1 | METHODS FOR THE APPLICATION IN THICK LAYER OF CEMENTITIOUS COMPOSITIONS COMPRISING KINETIC REGULATOR | SIKA TECHNOLOGY AG (CH) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024175602-A1 | LIGHTWEIGHT CEMENTITIOUS COMPOSITION HAVING KINETIC REGULATOR | SIKA TECHNOLOGY AG (CH) | 2024-08-29 | — | — | WO | disclosed |
| EP-4417587-A1 | METHODS FOR THE APPLICATION IN THICK LAYER OF CEMENTITIOUS COMPOSITIONS COMPRISING KINETIC REGULATOR | Sika Technology AG (CH) | 2024-08-21 | — | — | EP | disclosed |
| US-7863025-B2 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | CHEMIC LABORATORIES, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| EP-1802763-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF ALPHA-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | Chemic Laboratories, Inc (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20070082039-A1 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids, the use of the same as percutaneous permeation enhancers, and topical gels for the transdermal delivery of steroids | CHEMSMART, LLC | 2007-04-12 | — | — | US | disclosed |
| WO-2007038496-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF HYDROXY CARBOXYLIC ACIDS, THE USE OF THE SAME AS PERCUTANEOUS PERMEATION ENHANCERS | CHEMIC LABORATORIES, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2006044926-A2 | SYNTHESIS OF FATTY ALCOHOL ESTERS OF α-HYDROXY CARBOXYLIC ACIDS AND THEIR USE AS PERCUTANEOUS ABSORPTION ENHANCERS | CHEMIC LABORATORIES, INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084154-A1 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | CHEMIC LABORATORIES, LLC | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250064713-A1 | COSMETIC COMPOSITIONS | CUTA, SUCLG1, ASAH2 | NPC1 389/4885RAB9A 3295/4885SMN1; SMN2 2453/4885 |
| US-20060084154-A1 | Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers | ADH1A, ADH1C, FASN | NPC1 246/4885RAB9A 2086/4885SMN1; SMN2 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.