Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | NNMT | P40261 | 5/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207634 | 0.87 | MGAM (0.45) | HPGDSPSMD14MGAM | |
| SCHEMBL18009630 | 0.76 | NNMT (0.43) | HPGDSNNMTPSMD14STAMBPCOPS5 | |
| SCHEMBL17967334 | 0.71 | HPGDS (0.54) | HPGDSNNMTPSMD14STAMBPCOPS5 | |
| SCHEMBL7081027 | 0.69 | HPGDS (0.53) | HPGDSNNMTPSMD14STAMBPCOPS5 | |
| SCHEMBL528982 | 0.69 | TSHR (0.51) | SMN1; SMN2CHEK2CHEK1 | |
| SCHEMBL5405254 | 0.69 | HPGDS (0.55) | HPGDSNNMTPSMD14STAMBPCOPS5 | |
| Urea SCHEMBL6016094 | 0.67 | MGAM (0.47) | HPGDSPSMD14MGAMSMN1; SMN2CHEK2 | |
| SCHEMBL17967327 | 0.66 | HPGDS (0.64) | HPGDSNNMT | |
| SCHEMBL16517720 | 0.64 | HPGDS (0.50) | HPGDSNNMTPSMD14STAMBPCOPS5 | |
| SCHEMBL29362497 | 0.64 | MGAM (0.71) | HPGDSPSMD14STAMBPCOPS5MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |