Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223248 | 0.87 | HPGDS (0.44) | MGAMPSMD14HPGDS | |
| SCHEMBL5553780 | 0.77 | MGAM (0.51) | MGAMPSMD14PDGFRBPDGFRAKDM4E | |
| SCHEMBL19020851 | 0.77 | MGAM (0.51) | MGAMPSMD14POLBKDM4EALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28775857 | 0.76 | MGAM (0.50) | MGAMPSMD14PDGFRBPDGFRAKDM4E | |
| SCHEMBL8519849 | 0.74 | MGAM (0.63) | MGAMPSMD14PDGFRBPDGFRAPOLB | |
| Urea SCHEMBL6016094 | 0.74 | MGAM (0.47) | MGAMPSMD14PDGFRBPDGFRAKDM4E | |
| SCHEMBL10465589 | 0.73 | MGAM (0.58) | MGAMPSMD14PDGFRBPDGFRAPOLB | |
| SCHEMBL9425156 | 0.70 | MGAM (0.58) | MGAMPSMD14PDGFRBPDGFRAPOLB | |
| SCHEMBL3862277 | 0.68 | ALDH1A1 (0.50) | POLBKDM4EALDH1A1 | |
| SCHEMBL7086111 | 0.68 | MGAM (0.56) | MGAMPSMD14PDGFRBPDGFRAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |