SCHEMBL822333

SCHEMBL822333

Cc1ccc(C(=O)Nc2nc(C)nc(NC(=O)c3ccc(C)cc3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.58
NPC1 O15118 7/20 0.58
SMN1; SMN2 Q16637 6/20 0.55
TP53 P04637 1/20 0.55
ADORA2A P29274 3/20 0.54
ADORA1 P30542 2/20 0.54
ALDH1A1 P00352 3/20 0.53
GAA P10253 1/20 0.53
ADORA3 P0DMS8 2/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
KMT2A Q03164 4/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
RECQL P46063 1/20 0.51
PKM P14618 1/20 0.49
NAMPT P43490 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822043 0.89 MEN1 (0.69) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL822047 0.86 RAB9A (0.58) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL2623093 0.85 L3MBTL1 (0.64) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL821756 0.84 NPC1 (0.56) RAB9ANPC1SMN1; SMN2TP53HDAC1
SCHEMBL823202 0.83 KDM4E (0.75) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL2623094 0.81 ADORA1 (0.60) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL10073738 0.80 RAB9A (0.49) RAB9ANPC1SMN1; SMN2TP53ADORA2A
SCHEMBL821364 0.80 GRM5 (0.61) RAB9ANPC1SMN1; SMN2TP53HDAC6
SCHEMBL28288582 0.79 KMT2A (0.51) RAB9ANPC1SMN1; SMN2TP53ADORA1
SCHEMBL821716 0.78 KMT2A (0.60) RAB9ANPC1SMN1; SMN2TP53ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE CNKSR1, C1R, PNISR RAB9A 2981/4885NPC1 4696/4885SMN1; SMN2 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.