Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 8/20 | 0.50 |
| ▸ | IL6ST | P40189 | 5/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765149 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL4768353 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL8223849 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL14284199 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL4765096 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL4774119 | 0.84 | IL6ST (0.50) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL14523672 | 0.83 | IL6ST (0.58) | IDH1IL6STSTAT3 | |
| SCHEMBL9061436 | 0.81 | TSHR (0.52) | IL6STSTAT3PIK3CD | |
| SCHEMBL13308121 | 0.80 | IL6ST (0.49) | IDH1IL6STSTAT3PIK3CD | |
| SCHEMBL14960196 | 0.80 | IL6ST (0.49) | IDH1IL6STSTAT3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021024-A1 | Metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-01-24 | — | — | US | disclosed |
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021024-A1 | Metalloprotease inhibitors | MMP2, MMP9, MMP3 | IDH1 428/4885IL6ST 2563/4885STAT3 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.