SCHEMBL822362

SCHEMBL822362

CNc1cc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)nc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)n1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
LMNA P02545 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
MAPT P10636 1/20 0.54
HSD17B10 Q99714 1/20 0.54
POLB P06746 4/20 0.54
HTT P42858 1/20 0.54
KDM4E B2RXH2 2/20 0.53
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GAA P10253 1/20 0.49
MAPK1 P28482 1/20 0.49
TRPV4 Q9HBA0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821992 0.88 POLB (0.63) NPC1RAB9ALMNANPSR1MAPT
SCHEMBL15308188 0.85 CA2 (0.54) RAB9ANPSR1MAPTPOLBKDM4E
SCHEMBL821709 0.84 GAA (0.55) NPC1RAB9ALMNANPSR1MAPT
SCHEMBL822097 0.82 SMN1; SMN2 (0.43) NPC1RAB9AMAPTHSD17B10HTT
SCHEMBL822093 0.80 RAB9A (0.54) NPC1RAB9AMAPTPOLBKDM4E
SCHEMBL15308187 0.79 NNMT (0.46) NPC1RAB9AMAPTPOLBKDM4E
SCHEMBL821939 0.78 ADORA1 (0.56) NPC1RAB9AL3MBTL1
SCHEMBL821420 0.78 NPC1 (0.51) NPC1RAB9ALMNAMAPTHTT
SCHEMBL15308163 0.76 MEN1 (0.66) NPC1RAB9ALMNANPSR1MAPT
SCHEMBL15305676 0.76 CA2 (0.49) NPSR1MAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-20120268694-A1 CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-25 US disclosed
US-20120249933-A1 CELLULOSE ACYLATE FILM, ITS PRODUCTION METHOD, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-20120231217-A1 OPTICAL FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed