Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810804 | 0.83 | MAOA (0.71) | MAOAMAOBCYP3A4TDP1MAPT | |
| Maackiain SCHEMBL29670858 | 0.83 | MAOA (1.00) | MAOAMAOBCYP3A4TDP1MAPT | |
| SCHEMBL12891393 | 0.83 | MAOA (0.71) | MAOAMAOBCYP3A4TDP1MAPT | |
| Maackiain SCHEMBL12810278 | 0.83 | MAOA (1.00) | MAOAMAOBCYP3A4TDP1MAPT | |
| Pterocarpin SCHEMBL1248057 | 0.80 | MAPT (1.00) | MAOAMAOBCYP3A4TDP1MAPT | |
| Pterocarpin SCHEMBL1248055 | 0.80 | MAPT (1.00) | MAOAMAOBCYP3A4TDP1MAPT | |
| Pterocarpin SCHEMBL29361907 | 0.80 | MAPT (1.00) | MAOAMAOBCYP3A4TDP1MAPT | |
| Neodulin SCHEMBL29374942 | 0.74 | MAOA (0.58) | MAOAMAOBCYP3A4TDP1MAPT | |
| Neodulin SCHEMBL28407408 | 0.74 | MAOA (0.58) | MAOAMAOBCYP3A4TDP1MAPT | |
| Medicarpin SCHEMBL2812444 | 0.70 | MAOA (0.78) | MAOAMAOBCYP3A4TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058269-A2 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |