Maackiain

Maackiain

SCHEMBL29670858

Oc1ccc2c(c1)OC[C@H]1c3cc4c(cc3O[C@@H]21)OCO4

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 1.00
▸ MAOB P27338 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ MAPT P10636 1/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ TDP1 Q9NUW8 1/20 0.67
▸ PTPN1 P18031 3/20 0.55
▸ MGAM O43451 1/20 0.49
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maackiain SCHEMBL12810278 1.00 MAOA (1.00) MAOAMAOBCYP3A4MAPTMAPK1
Maackiain SCHEMBL28064249 1.00 MAOA (1.00) MAOAMAOBCYP3A4MAPTMAPK1
Demethylmedicarpin SCHEMBL29843376 0.88 MAOA (0.78) MAOAMAOBCYP3A4MAPTMAPK1
Medicarpin SCHEMBL2812444 0.88 MAOA (0.78) MAOAMAOBCYP3A4MAPTMAPK1
Demethylmedicarpin SCHEMBL31663447 0.88 MAOA (0.78) MAOAMAOBCYP3A4MAPTMAPK1
SCHEMBL8223903 0.83 MAOA (0.71) MAOAMAOBCYP3A4MAPTMAPK1
SCHEMBL12891393 0.83 MAOA (0.71) MAOAMAOBCYP3A4MAPTMAPK1
SCHEMBL12810804 0.83 MAOA (0.71) MAOAMAOBCYP3A4MAPTMAPK1
SCHEMBL232991 0.81 CYP3A4 (0.68) MAOAMAOBCYP3A4MAPTMAPK1
SCHEMBL19999737 0.81 MAOA (0.67) MAOAMAOBCYP3A4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4375914-B1 MINE MANAGEMENT SYSTEM HITACHI CONSTRUCTION MACH CO (JP) 2026-03-25 — — EP claimed
CN-118841188-A Mining method of stomach adenocarcinoma resisting action mechanism of Sixisan and application of mining method 江苏食品药品职业技术学院 2024-10-25 — — CN claimed
CN-114272323-A Traditional Chinese medicine formula for regulating and controlling intestinal function of lactating women 华子昂 2022-04-05 — — CN claimed
US-20250281559-A1 DRUG FOR TREATMENT OF BREAST CANCER WITH ANTLER AND GINSENG AS SOVEREIGN DRUG AND PREPARATION METHOD AND APPLICATION THEREOF JILIN UNIVERSITY (CN) 2025-09-11 — — US disclosed
EP-4438995-B1 PROTECTED VEHICLE RHEINMETALL LANDSYSTEME GMBH (DE) 2025-08-06 — — EP disclosed
EP-4463915-A1 TOOL AND CABLE CONNECTION DEVICE COMPRISING SAME HARTING Electric Stiftung & Co. KG (DE) 2024-11-20 — — EP disclosed
CN-118841188-A Mining method of stomach adenocarcinoma resisting action mechanism of Sixisan and application of mining method 江苏食品药品职业技术学院 2024-10-25 — — CN disclosed
EP-4438995-A1 ROLLOVER PROTECTION SYSTEM AND PROTECTED VEHICLE Rheinmetall Landsysteme GmbH (DE) 2024-10-02 — — EP disclosed
EP-3328761-B1 CONVEYING SYSTEM CONTITECH DEUTSCHLAND GMBH (DE) 2024-08-21 — — EP disclosed
EP-2703280-B2 Weapon clearing device for clearing weapons, such as mines, underwater, unmanned submarine with weapon clearing device and method for same ATLAS ELEKTRONIK GMBH (DE) 2024-06-05 — — EP disclosed
EP-4028715-B1 UNDERWATER VEHICLE COMPRISING TWO SHAPED CHARGES ARRANGED BEHIND ONE ANOTHER ATLAS ELEKTRONIK GMBH (DE) 2023-08-23 — — EP disclosed
WO-2023131373-A1 TOOL AND CABLE CONNECTION DEVICE COMPRISING SAME HARTING ELECTRIC STIFTUNG & CO. KG (DE) 2023-07-13 — — WO disclosed
EP-4028715-A1 UNDERWATER VEHICLE COMPRISING TWO SHAPED CHARGES ARRANGED BEHIND ONE ANOTHER ATLAS ELEKTRONIK GmbH (DE) 2022-07-20 — — EP disclosed
CN-114272323-A Traditional Chinese medicine formula for regulating and controlling intestinal function of lactating women 华子昂 2022-04-05 — — CN disclosed
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