Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221394 | 0.95 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8220785 | 0.94 | DRD4 (0.48) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL4575368 | 0.94 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8220527 | 0.93 | HTR7 (0.47) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8221639 | 0.93 | KMT2A (0.54) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8221642 | 0.93 | DRD4 (0.48) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8221246 | 0.92 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8213356 | 0.92 | HTR7 (0.48) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL4575198 | 0.92 | LMNA (0.46) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL4575074 | 0.91 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |