Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777843 | 0.93 | MAPK1 (0.37) | RENMAPK1 | |
| SCHEMBL3777847 | 0.93 | MAPK1 (0.37) | RENMAPK1 | |
| SCHEMBL12053876 | 0.88 | REN (0.44) | REN | |
| SCHEMBL3781911 | 0.88 | REN (0.44) | REN | |
| SCHEMBL3784116 | 0.88 | REN (0.44) | REN | |
| SCHEMBL8231860 | 0.87 | MAPK1 (0.35) | RENMAPK1 | |
| SCHEMBL12053964 | 0.87 | MAPK1 (0.38) | RENMAPK1 | |
| SCHEMBL8229690 | 0.86 | MAPK1 (0.38) | RENMAPK1 | |
| SCHEMBL12053981 | 0.86 | MAPK1 (0.38) | RENMAPK1 | |
| SCHEMBL12053985 | 0.83 | REN (0.40) | RENMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084485-B2 | 6-(aminoalkyl)indazoles | VITAE PHARMACEUTICALS, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100331287-A1 | 6-(Aminoalkyl)Indazoles | VITAE PHARMACEUTICALS, INC. | 2010-12-30 | — | — | US | disclosed |
| WO-2007120523-A2 | 6-(AMINOALKYL)INDAZOLES | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331287-A1 | 6-(Aminoalkyl)Indazoles | REN, AGTR1, AGTR2 | REN 1/4885MAPK1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.