Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 20/20 | 0.55 |
| ▸ | CTSS | P25774 | 20/20 | 0.55 |
| ▸ | CTSK | P43235 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347356 | 0.85 | CTSB (0.73) | CTSBCTSSCTSK | |
| SCHEMBL8227083 | 0.84 | CTSB (0.52) | CTSBCTSSCTSK | |
| SCHEMBL8223853 | 0.83 | CTSS (0.79) | CTSBCTSSCTSK | |
| SCHEMBL8218566 | 0.80 | CTSB (0.73) | CTSBCTSSCTSK | |
| SCHEMBL8223964 | 0.80 | CTSB (0.63) | CTSBCTSSCTSK | |
| SCHEMBL8223852 | 0.79 | CTSB (0.56) | CTSBCTSSCTSK | |
| SCHEMBL8224249 | 0.78 | CTSB (0.67) | CTSBCTSSCTSK | |
| SCHEMBL11917586 | 0.78 | CTSS (0.71) | CTSBCTSSCTSK | |
| SCHEMBL8220646 | 0.78 | CTSB (0.74) | CTSBCTSSCTSK | |
| SCHEMBL8225932 | 0.77 | CTSB (0.65) | CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137738-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-12-06 | — | — | WO | disclosed |