Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 18/20 | 0.67 |
| ▸ | CTSS | P25774 | 18/20 | 0.67 |
| ▸ | CTSK | P43235 | 18/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347053 | 0.85 | CTSS (0.92) | CTSBCTSSCTSK | |
| SCHEMBL8224300 | 0.82 | CTSB (0.54) | CTSBCTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL11917586 | 0.81 | CTSS (0.71) | CTSBCTSSCTSK | |
| SCHEMBL346799 | 0.80 | CTSS (1.00) | CTSBCTSSCTSK | |
| SCHEMBL8220646 | 0.80 | CTSB (0.74) | CTSBCTSSCTSK | |
| SCHEMBL8225932 | 0.80 | CTSB (0.65) | CTSBCTSSCTSK | |
| SCHEMBL8218566 | 0.79 | CTSB (0.73) | CTSBCTSSCTSK | |
| SCHEMBL8227148 | 0.79 | CTSB (0.76) | CTSBCTSSCTSK | |
| SCHEMBL13639479 | 0.78 | CTSS (0.74) | CTSBCTSSCTSK | |
| SCHEMBL8224286 | 0.78 | CTSB (0.55) | CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137738-A1 | SPIROCYCLIC NITRILES AS PROTEASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-12-06 | — | — | WO | disclosed |