SCHEMBL12987705

SCHEMBL12987705

CCCCCCCCCCCCCCCCCCOC(CO)C(O)C(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665594 0.88 ALDH1A1 (0.57) KDM4EDUSP3LMNA
SCHEMBL6718800 0.88 ALDH1A1 (0.57) KDM4EDUSP3LMNA
SCHEMBL7194283 0.88 ALDH1A1 (0.57) KDM4EDUSP3LMNA
SCHEMBL19521515 0.83 CES2 (0.47) CES2KDM4EDUSP3MEN1KMT2A
SCHEMBL8224464 0.81 MGAM (0.41) KDM4EDUSP3MEN1KMT2A
SCHEMBL9055070 0.81 PRKCA (0.50) CES2KDM4EDUSP3MEN1KMT2A
SCHEMBL9056642 0.81 MAPT (0.60) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9057592 0.81 MAPT (0.60) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9054459 0.81 MAPT (0.60) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9055217 0.81 MAPT (0.60) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2694044-A1 SYNERGISTIC COMPOSITIONS AND METHODS Lycored Ltd. (IL) 2014-02-12 EP disclosed
WO-2012137209-A1 SYNERGISTIC COMPOSITIONS AND METHODS LYCORED LTD (IL) 2012-10-11 WO disclosed