Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019207 | 0.79 | FFAR1 (0.50) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL27489436 | 0.78 | KDM4E (0.39) | KMT2AMEN1LMNAHPGDNPSR1 | |
| Phosphine SCHEMBL28777955 | 0.77 | KDM4E (0.39) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL29077373 | 0.76 | TAS1R3 (0.49) | KMT2AMEN1LMNATP53SMN1; SMN2 | |
| SCHEMBL25468277 | 0.76 | KMT2A (0.40) | KMT2AMEN1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL5997084 | 0.75 | HPGD (0.43) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL8839023 | 0.75 | HPGD (0.43) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL7587990 | 0.74 | ALDH1A1 (0.39) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL9170786 | 0.74 | HRH3 (0.60) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL10850810 | 0.73 | HRH3 (0.62) | KMT2AMEN1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033456-A1 | SPIRO-CONDENSED AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABILISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |