Phosphine

Phosphine

SCHEMBL28777955

CCC(C(=O)O)C(=O)c1c(C)cc(C)cc1C.P

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
CRHR1 P34998 1/20 0.38
NPSR1 Q6W5P4 2/20 0.36
HTT P42858 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
ITGB1 P05556 1/20 0.35
ITGA4 P13612 1/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7587990 0.86 ALDH1A1 (0.39) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL7589052 0.78 KDM4E (0.43) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL8224635 0.77 KMT2A (0.44) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL2290983 0.75 TAS1R3 (0.48) KDM4ESMN1; SMN2MEN1LMNAKMT2A
SCHEMBL2499316 0.74 KDM4E (0.36) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL2499307 0.74 KDM4E (0.36) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL28395253 0.73 KDM4E (0.38) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL15841100 0.72 KDM4E (0.37) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL10019207 0.71 FFAR1 (0.50) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1
SCHEMBL9121747 0.70 HPGD (0.41) KDM4ESMN1; SMN2HPGDL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101495569-B Resin composition, method for producing same, and molded article TEIJIN LTD 2012-05-30 CN disclosed
CN-101495569-A Resin composition, method for producing same, and molded article TEIJIN LTD (JP) 2009-07-29 CN disclosed