Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218968 | 0.84 | CACNA1B (0.35) | CACNA1BCCR2HTR2CMAPTALDH1A1 | |
| SCHEMBL8224367 | 0.84 | CACNA1B (0.35) | CACNA1BCCR2HTR2CMAPTALDH1A1 | |
| SCHEMBL8222248 | 0.83 | GAA (0.43) | CACNA1BALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL8224820 | 0.83 | CACNA1B (0.35) | CACNA1BMAPTALDH1A1GAAKDM4E | |
| SCHEMBL8223286 | 0.81 | CACNA1B (0.33) | CACNA1BMAPTALDH1A1GAAKDM4E | |
| SCHEMBL8222581 | 0.71 | KDM4E (0.48) | CACNA1BCCR2HTR2CMAPTALDH1A1 | |
| SCHEMBL27544295 | 0.71 | TSHR (0.46) | CACNA1BCCR2HTR2CMAPTALDH1A1 | |
| SCHEMBL8222583 | 0.71 | KDM4E (0.52) | CACNA1BCCR2HTR2CMAPTALDH1A1 | |
| SCHEMBL8222269 | 0.70 | GAA (0.47) | MAPTALDH1A1GAAMGAMAMY1A | |
| SCHEMBL8222265 | 0.70 | KDM4E (0.68) | HTR2CMAPTALDH1A1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |