Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829969 | 0.74 | NPSR1 (0.48) | SCN5ASCN9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL5420585 | 0.73 | POLB (0.49) | FAAHRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL10879703 | 0.73 | BCHE (0.50) | FAAH | |
| SCHEMBL8276051 | 0.72 | EPHX2 (0.58) | EPHX2FAAHSMN1; SMN2HPGDMEN1 | |
| SCHEMBL12267924 | 0.72 | SCN5A (0.65) | SCN5ASCN9ASMN1; SMN2 | |
| SCHEMBL3519625 | 0.72 | CNR1 (0.42) | EPHX2FAAHRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27648733 | 0.71 | RAB9A (0.44) | FAAHRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL11218133 | 0.71 | EPHX2 (0.79) | EPHX2RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL11618396 | 0.71 | KIF11 (0.49) | SCN5ASCN9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7377471 | 0.71 | EPHX2 (0.51) | EPHX2FAAHRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |