Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822421 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2ADGKACA12 | |
| SCHEMBL822422 | 0.94 | DNM1 (0.55) | DNM1MEN1KMT2ADGKACA12 | |
| SCHEMBL822710 | 0.93 | DNM1 (0.55) | DNM1MEN1KMT2ADGKACA12 | |
| SCHEMBL822615 | 0.92 | DNM1 (0.58) | DNM1MEN1KMT2ADGKACHRM2 | |
| SCHEMBL10030578 | 0.85 | DNM1 (0.56) | DNM1MEN1KMT2ADGKACHRM2 | |
| SCHEMBL16994180 | 0.84 | DNM1 (0.42) | DNM1MEN1KMT2ACA12CA1 | |
| SCHEMBL25868606 | 0.84 | DNM1 (0.53) | DNM1MEN1KMT2ADGKACA12 | |
| SCHEMBL8367998 | 0.84 | DNM1 (0.72) | DNM1DGKACA12CA1CA2 | |
| SCHEMBL13485577 | 0.82 | MEN1 (0.48) | DNM1MEN1KMT2ADGKACA12 | |
| SCHEMBL13485570 | 0.80 | DNM1 (0.46) | DNM1MEN1KMT2ADGKACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280912-A1 | DEGRADABLE POLYMER NANOSTRUCTURE MATERIALS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280912-A1 | DEGRADABLE POLYMER NANOSTRUCTURE MATERIALS | BCAT1, PCBP1, TRIM4 | DNM1 4409/4885MEN1 3841/4885KMT2A 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.