SCHEMBL822710

SCHEMBL822710

CCCC(=O)OCCOCCCCCCOCCOC(=O)CCN(C)CCOCCN(C)C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.55
DGKA P23743 1/20 0.44
NAAA Q02083 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
LTA4H P09960 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
THRB P10828 3/20 0.37
THRA P10827 2/20 0.37
HTR2C P28335 1/20 0.37
KDM4E B2RXH2 1/20 0.36
KDM5A P29375 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822615 0.94 DNM1 (0.58) DNM1DGKANAAALTA4HMEN1
SCHEMBL822421 0.94 DNM1 (0.53) DNM1DGKANAAACA12CA1
SCHEMBL822422 0.93 DNM1 (0.55) DNM1DGKANAAACA12CA1
SCHEMBL822525 0.93 DNM1 (0.54) DNM1DGKANAAACA12CA1
SCHEMBL10030578 0.82 DNM1 (0.56) DNM1DGKANAAALTA4HMEN1
SCHEMBL25868606 0.81 DNM1 (0.53) DNM1DGKACA12CA1CA2
Hydrochloric Acid SCHEMBL28572570 0.81 DNM1 (0.79) DNM1DGKANAAAMEN1KMT2A
Bromide SCHEMBL21351807 0.81 DNM1 (0.79) DNM1DGKANAAAMEN1KMT2A
SCHEMBL16994180 0.81 DNM1 (0.42) DNM1CA12CA1CA2CA9
SCHEMBL14208263 0.80 DGKA (0.70) DNM1DGKANAAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110280912-A1 DEGRADABLE POLYMER NANOSTRUCTURE MATERIALS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110280912-A1 DEGRADABLE POLYMER NANOSTRUCTURE MATERIALS BCAT1, PCBP1, TRIM4 DNM1 4409/4885DGKA 3286/4885NAAA 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.