Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225998 | 1.00 | GRIK1 (0.32) | GRIK1 | |
| SCHEMBL31147800 | 0.80 | GRIK1 (0.33) | GRIK1 | |
| SCHEMBL1658145 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL1658148 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL18893461 | 0.76 | GRIK1 (0.31) | GRIK1 | |
| SCHEMBL24588509 | 0.74 | — | — | |
| SCHEMBL8224498 | 0.74 | — | — | |
| SCHEMBL14423275 | 0.74 | — | — | |
| SCHEMBL8224493 | 0.74 | — | — | |
| SCHEMBL1659162 | 0.74 | ALOX15 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349859-B | Cyclopropane compounds | 花王株式会社 | 2022-01-11 | — | — | CN | disclosed |
| EP-3375770-B1 | CYCLOPROPANE COMPOUND | KAO CORP (JP) | 2020-06-03 | — | — | EP | disclosed |
| US-20190055179-A1 | CYCLOPROPANE COMPOUND | KAO CORPORATION (JP) | 2019-02-21 | — | — | US | disclosed |
| US-20190055179-A1 | CYCLOPROPANE COMPOUND | KAO CORPORATION (JP) | 2019-02-21 | — | — | US | disclosed |
| EP-3375770-A1 | CYCLOPROPANE COMPOUND | Kao Corporation (JP) | 2018-09-19 | — | — | EP | disclosed |
| US-20130065969-A9 | Odour Compounds | GIVAUDAN SA (CH) | 2013-03-14 | — | — | US | disclosed |
| US-20120184630-A1 | Odour Compounds | KRAFT PHILIP (CH) | 2012-07-19 | — | — | US | disclosed |
| EP-2475639-A2 | ODOUR COMPOUNDS | Givaudan SA (CH) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029895-A2 | ODOUR COMPOUNDS | GIVAUDAN SA (CH) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055179-A1 | CYCLOPROPANE COMPOUND | CNR1, TRPA1, TRPV1 | GRIK1 2976/4885 |
| US-20130065969-A9 | Odour Compounds | PRMT9, PRMT5, PRMT1 | GRIK1 1164/4885 |
| US-20120184630-A1 | Odour Compounds | PRMT9, PRMT5, PRMT1 | GRIK1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.