Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220990 | 0.83 | THRB (0.57) | THRBHDAC1NPC1RAB9AHDAC6 | |
| SCHEMBL8226268 | 0.81 | THRB (0.57) | THRBHDAC1NPC1HDAC6MEN1 | |
| SCHEMBL8226117 | 0.81 | THRB (0.55) | THRBHDAC1NPC1RAB9A | |
| SCHEMBL8225963 | 0.79 | THRB (0.58) | THRBHDAC1 | |
| SCHEMBL8219815 | 0.79 | THRB (0.61) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8226125 | 0.78 | THRB (0.65) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8229448 | 0.78 | THRB (0.59) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8226183 | 0.77 | THRB (0.66) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8228692 | 0.77 | THRB (0.66) | THRBHDAC1NPC1 | |
| SCHEMBL8225959 | 0.77 | THRB (0.54) | THRBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |