Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678812 | 0.80 | CA2 (0.67) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9908320 | 0.78 | PSIP1 (0.68) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL172035 | 0.78 | CA2 (0.64) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL330720 | 0.78 | CA2 (0.64) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL451007 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL344067 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3248478 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1563238 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1589447 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6038843 | 0.76 | CA2 (0.61) | CA2UCHL1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |