Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.67 |
| ▸ | MPO | P05164 | 12/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1243023 | 0.85 | GPR84 (0.65) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL8297901 | 0.81 | GPR84 (0.73) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL30482437 | 0.80 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL18383118 | 0.80 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL30913603 | 0.80 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL8223121 | 0.79 | GPR84 (0.65) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL30969154 | 0.78 | MPO (0.75) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL2406225 | 0.78 | MPO (0.71) | GPR84MPOHTR2ATRPM8HTR2C | |
| SCHEMBL2122451 | 0.78 | MPO (0.75) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL23269531 | 0.77 | GPR84 (0.73) | GPR84MPOHTR2ATRPM8HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040974-A1 | INDOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |