Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 7/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358682 | 0.79 | GPR84 (0.71) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL8226546 | 0.79 | GPR84 (0.67) | GPR84HTR1AHTR2AHTR2CMPO | |
| Iodide SCHEMBL1243023 | 0.78 | GPR84 (0.65) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL13715348 | 0.76 | GPR84 (0.67) | GPR84HTR1AHTR2AMPOTRPM8 | |
| SCHEMBL29445177 | 0.75 | GPR84 (0.65) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL23259357 | 0.75 | GPR84 (0.65) | GPR84HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL8222885 | 0.75 | GPR84 (0.65) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL13715692 | 0.74 | GPR84 (0.69) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL2539018 | 0.74 | GPR84 (0.69) | GPR84HTR1AHTR2AHTR2CMPO | |
| SCHEMBL24912883 | 0.74 | HTR2A (0.69) | GPR84HTR1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040974-A1 | INDOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |