Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812044 | 0.94 | PTPN11 (0.42) | PTPN11CYSLTR2CYSLTR1S1PR3PTPN1 | |
| SCHEMBL12924831 | 0.91 | PTPN11 (0.38) | PTPN11CYSLTR2CYSLTR1S1PR3PTPN1 | |
| SCHEMBL10299949 | 0.88 | PTPN11 (0.40) | PTPN11CYSLTR2CYSLTR1S1PR3PTPN1 | |
| SCHEMBL12924865 | 0.86 | PTPN11 (0.41) | PTPN11S1PR3PTPN1PTPN6LMNA | |
| SCHEMBL12924858 | 0.84 | LPL (0.33) | PTPN11S1PR3PTPN1PTPN6LMNA | |
| SCHEMBL12924854 | 0.84 | LMNA (0.43) | PTPN11S1PR3PTPN1PTPN6LMNA | |
| SCHEMBL13400867 | 0.84 | PTPN11 (0.41) | PTPN11S1PR3PTPN1PTPN6LMNA | |
| SCHEMBL13494970 | 0.84 | PTPN11 (0.41) | PTPN11S1PR3PTPN1PTPN6LMNA | |
| SCHEMBL13429583 | 0.83 | MAPT (0.42) | PTPN11CYSLTR2CYSLTR1S1PR3PTPN1 | |
| SCHEMBL12924833 | 0.82 | L3MBTL1 (0.37) | PTPN11S1PR3PTPN1PTPN6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010359-A1 | SALICYLATE SUBSTITUTED CONJUGATED POLYMERS AND DEVICES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |