SCHEMBL822686

SCHEMBL822686

O=S(=O)(c1ccc(O)cc1)c1ccc(-c2ccc(SCCOC3CCCCO3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 5/20 0.36
CA12 O43570 4/20 0.36
CA1 P00915 4/20 0.36
CA9 Q16790 4/20 0.36
KDM4C Q9H3R0 1/20 0.34
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 2/20 0.34
NR2F2 P24468 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
NPC1 O15118 1/20 0.32
KDM2B Q8NHM5 1/20 0.32
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822684 0.87 MEN1 (0.47) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL822699 0.87 MEN1 (0.47) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL9785546 0.87 MEN1 (0.45) MEN1KMT2ACA2CA12CA1
SCHEMBL822704 0.85 MEN1 (0.34) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL20924566 0.80 MEN1 (0.41) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL8740886 0.77 GAA (0.42) MEN1KMT2ACA2CA12CA1
SCHEMBL822693 0.77 MEN1 (0.55) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL811405 0.75 MEN1 (0.42) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL822700 0.72 MEN1 (0.50) MEN1KMT2AKDM4CALDH1A1SMN1; SMN2
SCHEMBL7452792 0.72 KDM4C (0.44) MEN1KMT2AKDM4CALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390684-B1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KK (JP) 2019-04-24 EP disclosed
US-8829230-B2 Optical element compound, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2014-09-09 US disclosed
US-8829230-B2 Optical element compound, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2014-09-09 US disclosed
US-20140031582-A1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-01-30 US disclosed
US-20140031582-A1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-01-30 US disclosed
US-8569541-B2 Optical element compound, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2013-10-29 US disclosed
US-8569541-B2 Optical element compound, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2013-10-29 US disclosed
US-20110288330-A1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288330-A1 OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CENPE, AXIN2, CCNE2 MEN1 1609/4885KMT2A 1605/4885CA2 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.