Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228785 | 0.83 | ROCK2 (0.50) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL14972646 | 0.81 | CSNK2A2 (0.54) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL2744088 | 0.80 | SLC22A12 (0.53) | RXRARXRBPOLBRARBRARA | |
| SCHEMBL7112789 | 0.80 | GRIK1 (0.56) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL25126172 | 0.79 | RXRA (0.59) | RXRARXRBALDH1A1RAB9ANPC1 | |
| SCHEMBL10629220 | 0.78 | KDM4E (0.48) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL9003592 | 0.78 | KDM4E (0.48) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL30269683 | 0.77 | GAA (0.61) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL3131960 | 0.77 | GAA (0.61) | RXRARXRBALDH1A1KDM4EGAA | |
| SCHEMBL16798167 | 0.77 | RARB (0.57) | RXRARXRBALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087442-A2 | SUBSTITUTED BIARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |