Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219194 | 0.77 | SIGMAR1 (0.41) | CACNA1HRECQLSLC6A2SLC6A4OPRK1 | |
| SCHEMBL8221209 | 0.73 | CACNA1H (0.70) | CACNA1HALDH1A1 | |
| SCHEMBL12777762 | 0.68 | TSHR (0.35) | CACNA1HMAPTRECQLKDM4EALDH1A1 | |
| SCHEMBL6025678 | 0.62 | LIG1 (0.38) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL6025232 | 0.62 | LIG1 (0.38) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL6024476 | 0.62 | LIG1 (0.38) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL23466168 | 0.60 | LIG1 (0.42) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL21418971 | 0.60 | LIG1 (0.42) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL21418957 | 0.60 | LIG1 (0.42) | TDP1RECQLSLC6A2SLC6A4 | |
| SCHEMBL17725137 | 0.60 | LIG1 (0.42) | TDP1RECQLSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033456-A1 | SPIRO-CONDENSED AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABILISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |