Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.55 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228641 | 0.99 | THRB (0.54) | THRBWDR5MC4RHDAC1HTR1A | |
| SCHEMBL8228577 | 0.88 | THRB (0.65) | THRBMC4RHDAC1HTR1ADRD2 | |
| SCHEMBL8220990 | 0.87 | THRB (0.57) | THRBWDR5HDAC1 | |
| SCHEMBL8229336 | 0.86 | THRB (0.55) | THRBMC4RHDAC1 | |
| SCHEMBL8225252 | 0.85 | THRB (0.55) | THRBHDAC1 | |
| SCHEMBL8228692 | 0.84 | THRB (0.66) | THRBHDAC1HTR1ADRD2HTR2A | |
| SCHEMBL8227623 | 0.82 | THRB (0.68) | THRB | |
| SCHEMBL8229338 | 0.81 | THRB (0.62) | THRB | |
| SCHEMBL8225456 | 0.79 | THRB (0.70) | THRB | |
| SCHEMBL8219823 | 0.77 | THRB (0.63) | THRBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |