⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23101930 | 0.79 | — | — | |
| SCHEMBL22081828 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL38006 | 0.76 | — | — | |
| SCHEMBL2176867 | 0.76 | — | — | |
| SCHEMBL22356911 | 0.74 | — | — | |
| SCHEMBL23651374 | 0.73 | — | — | |
| SCHEMBL6990593 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL30227151 | 0.72 | ALDH1A1 (0.50) | — | |
| SCHEMBL22081826 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL583189 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4664755-A | Process for the purification of crude β-phenylethyl alcohol | HAARMAN & REIMER GMBH (DE) | 1987-05-12 | — | — | US | claimed |
| WO-2024054843-A2 | LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS | Acuitas Therapeutics, Inc. (CA) | 2024-03-14 | — | — | WO | disclosed |
| EP-3157895-B1 | FULLERENE DERIVATIVES FOR ORGANIC SEMICONDUCTORS | NANO C INC (US) | 2021-12-29 | — | — | EP | disclosed |
| US-11142769-B2 | Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability | BONAC CORPORATION (JP) | 2021-10-12 | — | — | US | disclosed |
| US-10040823-B2 | In vivo methods of monitoring biodistribution | KODE BIOTECH LIMITED (NZ) | 2018-08-07 | — | — | US | disclosed |
| US-20180037605-A1 | SYNTHETIC PEPTIDES AND ENZYMATIC FORMATION OF INTRACELLULAR HYDROGELS | BRANDEIS UNIVERSITY | 2018-02-08 | — | — | US | disclosed |
| US-20170240597-A1 | VIVO METHODS OF MONITORING BIODISTRIBUTION | KODE BIOTECH LIMITED (NZ) | 2017-08-24 | — | — | US | disclosed |
| US-9493485-B2 | Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof | IMAGO PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-20150307518-A1 | SPIROCYCLIC DIHYDRO-THIAZINE AND DIHYDRO-OXAZINE BACE INHIBITORS, AND COMPOSITIONS AND USES THEREOF | ELAN PHARMACEUTICALS, INC. | 2015-10-29 | — | — | US | disclosed |
| US-20150087825-A1 | SPIROCYCLIC DIGYDRO-THIAZINE AND DIHYDRO-OXAZINE BACE INHIBITORS, AND COMPOSITIONS AND USES THEREOF | XU YING-ZI (US) | 2015-03-26 | — | — | US | disclosed |
| EP-2046787-B1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LTD (GB) | 2011-04-06 | — | — | EP | disclosed |
| US-20090325952-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LIMITED | 2009-12-31 | — | — | US | disclosed |
| WO-2008015416-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008003443-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
| EP-0185249-B1 | PROCESS FOR THE PURIFICATION OF CRUDE BETA-PHENYLETHYL ALCOHOL | HAARMANN & REIMER GMBH (DE) | 1990-10-03 | — | — | EP | disclosed |
| US-4664755-A | Process for the purification of crude β-phenylethyl alcohol | HAARMAN & REIMER GMBH (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0185249-A2 | Process for the purification of crude beta-phenylethyl alcohol | HAARMANN & REIMER GMBH (DE) | 1986-06-25 | — | — | EP | disclosed |