⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38006 | 0.76 | — | — | |
| SCHEMBL30227151 | 0.72 | ALDH1A1 (0.50) | — | |
| SCHEMBL8228599 | 0.71 | — | — | |
| SCHEMBL4318488 | 0.69 | ALDH1A1 (0.47) | — | |
| SCHEMBL9151652 | 0.69 | — | — | |
| SCHEMBL19381 | 0.69 | — | — | |
| SCHEMBL16671676 | 0.69 | — | — | |
| SCHEMBL5087641 | 0.69 | — | — | |
| SCHEMBL102085 | 0.69 | — | — | |
| SCHEMBL5720348 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011218-A1 | POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF | BROWN UNIVERSITY (US) | 2024-01-11 | — | — | WO | disclosed |
| CN-113057942-A | Nano-particles containing hydrophobic drug, composition and application thereof | 正大天晴药业集团股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| EP-2288340-B1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-2416650-B1 | NANOPARTICLE FORMULATIONS AND USES THEROF | ABRAXIS BIOSCIENCE LLC (US) | 2020-02-26 | — | — | EP | disclosed |
| CN-105727303-B | A kind of high albumin composition for carrying Cabazitaxel drug and its preparation and preparation method | 四川科伦药物研究院有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20180289620-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2018-10-11 | — | — | US | disclosed |
| US-20170172975-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2017-06-22 | — | — | US | disclosed |
| CN-105727303-A | Albumin composition highly-carrying cabazitaxel medicine, preparation and preparation method thereof | 四川科伦药物研究院有限公司 | 2016-07-06 | — | — | CN | disclosed |
| US-20140302157-A1 | NANOPARTICLE FORMULATIONS AND USES THEROF | ABRAXIS BIOSCIENCE, LLC (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140080901-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2014-03-20 | — | — | US | disclosed |
| EP-2288340-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | Abraxis BioScience, LLC (US) | 2011-03-02 | — | — | EP | disclosed |
| WO-2010118365-A1 | NANOPARTICLE FORMULATIONS AND USES THEROF | ABRAXIS BIOSCIENCE, LLC (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20090263483-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2009-10-22 | — | — | US | disclosed |
| WO-2009126401-A1 | COMPOSITIONS OF HYDROPHOBIC TAXANE DERIVATIVES AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126938-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCES, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126175-A1 | COMPOSITIONS OF HYDROPHOBIC TAXANE DERIVATIVES AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| US-5086045-A | Antitumor antibiotic | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5028536-A | Biosynthesis | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0387860-A2 | Antitumor antibiotic BMY-41339 | Bristol-Myers Squibb Company (US) | 1990-09-19 | — | — | EP | disclosed |
| US-4863988-A | CHLORINATED GRAFT-MODIFIED POLYPROPYLENE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-09-05 | — | — | US | disclosed |