Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647037 | 0.86 | ABL1 (0.52) | ABL1GSK3B | |
| SCHEMBL645418 | 0.84 | ABL1 (0.48) | ABL1PIK3CAGSK3B | |
| SCHEMBL646571 | 0.84 | ABL1 (0.48) | ABL1PIK3CADYRK1AGSK3B | |
| SCHEMBL647015 | 0.83 | ADORA3 (0.47) | ABL1PIK3CAGSK3B | |
| SCHEMBL647637 | 0.80 | SMN1; SMN2 (0.44) | RXRAKDRCLK2HIPK4SRPK1 | |
| SCHEMBL646580 | 0.80 | DEGS1 (0.45) | ABL1DYRK1AGSK3B | |
| SCHEMBL645754 | 0.79 | HPGDS (0.40) | KDRCLK2HIPK4SRPK1CLK4 | |
| SCHEMBL645596 | 0.79 | MEN1 (0.44) | ABL1 | |
| SCHEMBL646895 | 0.79 | HPGDS (0.41) | RXRA | |
| SCHEMBL647154 | 0.78 | RAB9A (0.43) | KDRCLK2HIPK4SRPK1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109362-A2 | BENZOIMIDAZOLYL-PARAZINE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-27 | — | — | WO | disclosed |