Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.53 |
| ▸ | DRD4 | P21917 | 11/20 | 0.53 |
| ▸ | DRD3 | P35462 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233390 | 0.90 | DRD2 (0.65) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8229460 | 0.89 | DRD2 (0.55) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8229125 | 0.88 | DRD3 (0.55) | DRD2DRD4DRD3MAPTHTR1A | |
| SCHEMBL3978987 | 0.87 | DRD4 (0.52) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8223703 | 0.86 | DRD3 (0.54) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8229491 | 0.86 | DRD2 (0.67) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL8231863 | 0.85 | DRD3 (0.60) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL13484916 | 0.85 | HTR1A (0.60) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL3977786 | 0.85 | DRD3 (0.57) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL3981534 | 0.84 | MEN1 (0.58) | DRD2DRD4DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009741-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | PIERRE FABRE MEDICAMENT (FR) | 2008-01-24 | — | — | WO | disclosed |