SCHEMBL8229203 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CTSK	P43235	9/20	0.43

▸	CTSL	P07711	5/20	0.40

▸	CTSB	P07858	5/20	0.40

▸	CTSH	P09668	3/20	0.40

▸	LTA4H	P09960	1/20	0.40

▸	GRN	P28799	1/20	0.40

▸	SORT1	Q99523	1/20	0.40

▸	CTSS	P25774	2/20	0.40

▸	CPB2	Q96IY4	4/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13957700	0.86	GRN (0.49)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL13672872	0.84	GRN (0.41)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL13038259	0.84	GRN (0.41)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL22133208	0.82	CTSK (0.45)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL16327608	0.82	CTSK (0.45)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL7207942	0.81	REN (0.44)	CTSKCTSLCTSBLTA4HGRN
SCHEMBL18435239	0.81	CTSK (0.44)	CTSKCTSLCTSBCTSHCPB2
SCHEMBL13707910	0.81	CTSK (0.44)	CTSKCTSLCTSBCTSHCPB2
SCHEMBL16171793	0.81	CTSK (0.44)	CTSKCTSLCTSBCTSHLTA4H
SCHEMBL13337029	0.81	CTSK (0.44)	CTSKCTSLCTSBCTSHLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007117560-A2	PIPERIDINE AND MORPHOLINE RENIN INHIBITORS	VITAE PHARMACEUTICALS, INC. (US)	2007-10-18	—	—	WO	disclosed