Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511128 | 0.86 | GRN (0.55) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL7843875 | 0.86 | GRN (0.55) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL6467188 | 0.86 | GRN (0.55) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL20994281 | 0.84 | GRN (0.52) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL20994283 | 0.84 | GRN (0.52) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL13038259 | 0.83 | GRN (0.41) | GRNSORT1CTSKCTSSCTSL | |
| SCHEMBL13672872 | 0.83 | GRN (0.41) | GRNSORT1CTSKCTSSCTSL | |
| SCHEMBL8229203 | 0.81 | CTSK (0.43) | GRNSORT1CTSKCTSSCTSL | |
| SCHEMBL23052492 | 0.80 | REN (0.44) | RENGRNSORT1CTSKCTSS | |
| SCHEMBL19270372 | 0.80 | MMP1 (0.51) | RENCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934923-B1 | OPTICALLY ACTIVE ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ESTERS AND PROCESS FOR PREPARING SAID ESTERS | NIPPON KAYAKU KK (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6063955-A | OXIDIZING A THREO OR THREO-ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ACID ESTER, OPTICALLY ACTIVE AT 3-POSITION TO PRODUCE AN OPTICALLY ACTIVE 3-AMINO-2-OXOBUTYRIC ESTER, REDUCING ERYTHRO-SELECTIVELY CARBONYL GROUP AT 2-POSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0934923-A1 | OPTICALLY ACTIVE ERYTHRO-3-AMINO-2-HYDROXYBUTYRIC ESTERS AND PROCESS FOR PREPARING SAID ESTERS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |