Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.64 |
| ▸ | MGLL | Q99685 | 5/20 | 0.59 |
| ▸ | FAAH | O00519 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165630 | 1.00 | PTGS1 (0.64) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL5161619 | 0.93 | MGLL (0.54) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL2499154 | 0.86 | PTGS1 (0.68) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL5165436 | 0.85 | KAT2B (0.49) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL13052036 | 0.85 | PTGS1 (0.58) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL13447464 | 0.84 | PTGS1 (0.66) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL13338084 | 0.84 | PTGS1 (0.66) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL28038312 | 0.84 | PTGS1 (0.66) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL2992781 | 0.84 | PTGS1 (0.66) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL16579831 | 0.83 | PTGS1 (0.60) | PTGS1PTGS2MGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212113-A1 | AFFINITY ILLUDOFULVENE CONJUGATES | AF Chemicals, LLC, (US) | 2023-07-06 | — | — | US | disclosed |
| US-20210252160-A1 | COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | IL-2RX | 2021-08-19 | — | — | US | disclosed |
| WO-2021056754-A1 | METHOD FOR PREPARING ANTIBODY-DRUG CONJUGATE INTERMEDIATE BY MEANS OF ACID METHOD AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-04-01 | — | — | WO | disclosed |
| CN-107163134-B | Thymalfasin polyethylene glycol polymer, pharmaceutical composition containing same and application | 广州维奥康药业科技有限公司 | 2021-03-23 | — | — | CN | disclosed |
| US-10912841-B2 | Antibody-drug-conjugate and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2021-02-09 | — | — | US | disclosed |
| US-20200087297-A1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2020-03-19 | — | — | US | disclosed |
| EP-2910573-B1 | ANTIBODY-DRUG CONJUGATE PRODUCED BY BINDING THROUGH LINKER HAVING HYDROPHILIC STRUCTURE | DAIICHI SANKYO CO LTD (JP) | 2020-02-19 | — | — | EP | disclosed |
| CN-107163134-A | A kind of thymalfasin polyethylene glycol polymer, the pharmaceutical composition comprising it and application | 广州维奥康药业科技有限公司 | 2017-09-15 | — | — | CN | disclosed |
| US-20110282009-A1 | Free-radical Curable Isobutylene-rich Polymers | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-11-17 | — | — | US | disclosed |
| EP-1582548-B1 | PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER | DAINIPPON INK & CHEMICALS (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-7141642-B2 | Process for producing polymerizable polybranched polyester | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-11-28 | — | — | US | disclosed |
| US-20060047140-A1 | Process for producing polymerizable polybranched polyester | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-03-02 | — | — | US | disclosed |
| EP-1582548-A1 | PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212113-A1 | AFFINITY ILLUDOFULVENE CONJUGATES | OGFR, TNFSF11, FCER2 | PTGS1 3821/4885PTGS2 3952/4885MGLL 2696/4885 |
| US-10912841-B2 | Antibody-drug-conjugate and its use for the treatment of cancer | DDOST, DAD1, KRTCAP2 | PTGS1 4290/4885PTGS2 4449/4885MGLL 2845/4885 |
| US-20210252160-A1 | COMPOUNDS, COMPOSITIONS, METHODS, AND USES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | TNFRSF9, EGFR, NGFR | PTGS1 2207/4885PTGS2 2612/4885MGLL 3096/4885 |
| US-20060047140-A1 | Process for producing polymerizable polybranched polyester | ACSL4, ACSL1, HACL2 | PTGS1 2078/4885PTGS2 1332/4885MGLL 33/4885 |
| US-20200087297-A1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | H1-5, H1-4, CD47 | PTGS1 4848/4885PTGS2 4864/4885MGLL 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.