Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 4/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171231 | 0.77 | ADAM10 (0.42) | ADAM10ERBB2MMP2HRH3MMP1 | |
| SCHEMBL8190780 | 0.72 | ADAM10 (0.51) | ADAM10ERBB2MMP1PIM1 | |
| SCHEMBL8199546 | 0.72 | ADAM10 (0.51) | ADAM10ERBB2MMP1PIM1 | |
| Hydrochloric Acid SCHEMBL4406305 | 0.71 | ADAM10 (0.50) | ADAM10ERBB2MMP1PIM1 | |
| SCHEMBL2098678 | 0.70 | ADAM10 (0.49) | ADAM10ERBB2MMP1HSD11B1CYP2C9 | |
| SCHEMBL2098675 | 0.70 | ADAM10 (0.49) | ADAM10ERBB2MMP1HSD11B1CYP2C9 | |
| SCHEMBL416579 | 0.70 | ADAM10 (0.49) | ADAM10ERBB2MMP1HSD11B1CYP2C9 | |
| SCHEMBL7857753 | 0.70 | ADAM10 (0.49) | ADAM10ERBB2MMP1HSD11B1CYP2C9 | |
| SCHEMBL2098781 | 0.70 | ADAM10 (0.49) | ADAM10ERBB2MMP1HSD11B1CYP2C9 | |
| SCHEMBL9641197 | 0.69 | CHRNB2 (0.38) | CYP2C9PIM1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139585-A1 | CONTROLLED-RELEASE FORMULATION | SCHERING CORPORATION (US) | 2007-12-06 | — | — | WO | disclosed |