Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26841012 | 0.90 | HDAC8 (0.66) | HDAC8HDAC6SRD5A2HTTHPGD | |
| SCHEMBL8239806 | 0.84 | ADRB2 (0.48) | HDAC8HDAC6MAPK1HPGDGABBR2 | |
| SCHEMBL9906971 | 0.84 | MAPK1 (0.50) | SRD5A2MAPK1HTTHPGDCYP2C9 | |
| SCHEMBL7995537 | 0.82 | SRD5A2 (0.48) | SRD5A2MAPK1HTTHPGDCYP2C9 | |
| SCHEMBL3151943 | 0.80 | CNR1 (0.60) | SRD5A2MAPK1HPGDCYP2C9LMNA | |
| SCHEMBL8010830 | 0.80 | SRD5A2 (0.46) | SRD5A2MAPK1HTTHPGDCYP2C9 | |
| SCHEMBL11321913 | 0.78 | GABBR2 (0.69) | GABBR2GABBR1CYP2C9LMNACYP2C19 | |
| SCHEMBL22193617 | 0.78 | GABBR2 (0.69) | GABBR2GABBR1CYP2C9LMNACYP2C19 | |
| SCHEMBL29307505 | 0.77 | ALDH1A1 (0.53) | HDAC8HDAC6HTTHPGDMEN1 | |
| SCHEMBL8011236 | 0.77 | MAPK1 (0.43) | SRD5A2MAPK1HTTHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390241-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-11-30 | — | — | EP | disclosed |