Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230227 | 0.90 | KMT2A (0.35) | LMNAEPHX2BCHEACHEMEN1 | |
| SCHEMBL12928359 | 0.83 | ALDH1A1 (0.52) | LMNAEPHX2BCHEACHEALDH1A1 | |
| SCHEMBL25836455 | 0.80 | EPHX2 (0.56) | LMNAEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL5209042 | 0.80 | LMNA (0.40) | LMNAEPHX2BCHEACHEALDH1A1 | |
| SCHEMBL3203690 | 0.79 | MEN1 (0.40) | LMNAEPHX2BCHEACHEMEN1 | |
| SCHEMBL17285706 | 0.79 | EPHX2 (0.39) | LMNAEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL5211071 | 0.75 | MEN1 (0.36) | LMNAEPHX2BCHEACHEMEN1 | |
| SCHEMBL24671536 | 0.74 | MEN1 (0.33) | LMNAMEN1KMT2ATP53GABRP | |
| SCHEMBL2294523 | 0.74 | LMNA (0.81) | LMNAALDH1A1MEN1KMT2ASOAT1 | |
| SCHEMBL2370131 | 0.73 | ALDH1A1 (0.37) | LMNAEPHX2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |