Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22606744 | 0.79 | HCAR3 (0.54) | HCAR3RAB9AMAPTPDE10AKDM4E | |
| SCHEMBL6645913 | 0.78 | MAPT (0.53) | HCAR3RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL1853871 | 0.78 | HCAR3 (0.57) | HCAR3RAB9AMAPTPDE10AKDM4E | |
| SCHEMBL28334037 | 0.78 | HCAR3 (0.57) | HCAR3RAB9AMAPTPDE10AKDM4E | |
| SCHEMBL24616542 | 0.77 | HCAR3 (0.53) | HCAR3RAB9APDE10AKDM4EALDH1A1 | |
| SCHEMBL22606741 | 0.77 | HCAR3 (0.53) | HCAR3RAB9AMAPTPDE10AALDH1A1 | |
| SCHEMBL81827 | 0.76 | HCAR3 (0.55) | HCAR3RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL20613270 | 0.75 | RAB9A (0.50) | RAB9AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL14985165 | 0.75 | RAB9A (0.55) | RAB9AMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL23182690 | 0.75 | RAB9A (0.50) | RAB9AMAPTKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110577527-A | Method for synthesizing formyl substituted imidazo [1,2a ] pyridine compound | 浙江工业大学 | 2019-12-17 | — | — | CN | disclosed |
| EP-0569701-B1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 2000-09-27 | — | — | EP | disclosed |
| US-5463065-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5332824-A | Process for the preparation of 2-amino-5-methyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| EP-0569701-A1 | Process for preparation of 2-amino-5-methyl-pyridine | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |