Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035712 | 0.85 | LMNA (0.44) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL10066895 | 0.85 | LMNA (0.44) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL8226641 | 0.78 | EHMT2 (0.40) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL1607377 | 0.70 | LMNA (0.51) | KMT2AHPGDMEN1EHMT2EHMT1 | |
| SCHEMBL26006077 | 0.70 | ALDH1A1 (0.49) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL10035713 | 0.70 | HPGD (0.40) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL256693 | 0.68 | EHMT2 (0.48) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL4120039 | 0.68 | ALDH1A1 (0.50) | KMT2AHPGDMEN1EHMT2EHMT1 | |
| SCHEMBL7812413 | 0.67 | EHMT2 (0.47) | KMT2AHPGDMEN1TSHREHMT2 | |
| SCHEMBL464425 | 0.67 | HPGD (0.49) | KMT2AHPGDMEN1TSHREHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006113-A2 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2008-01-10 | — | — | WO | disclosed |