SCHEMBL1607377

SCHEMBL1607377

CCC(=O)Sc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
ALDH1A1 P00352 8/20 0.49
EHMT2 Q96KQ7 1/20 0.47
EHMT1 Q9H9B1 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
SMN1; SMN2 Q16637 6/20 0.46
RAB9A P51151 5/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 3/20 0.46
NPC1 O15118 3/20 0.46
KDM4E B2RXH2 1/20 0.46
ALOX15 P16050 1/20 0.46
KMT2A Q03164 3/20 0.45
MAPT P10636 1/20 0.45
MEN1 O00255 1/20 0.45
PKM P14618 1/20 0.45
POLB P06746 2/20 0.44
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4120039 0.86 ALDH1A1 (0.50) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL535804 0.84 ALDH1A1 (0.49) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL2902840 0.83 LMNA (0.48) LMNAALDH1A1SMN1; SMN2RAB9ANPC1
SCHEMBL2912510 0.82 LMNA (0.49) LMNAALDH1A1SMN1; SMN2RAB9ANPC1
SCHEMBL419934 0.82 LMNA (0.52) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL20061725 0.81 ALDH1A1 (0.49) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL20123198 0.81 KMT2A (0.45) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL13979666 0.81 LMNA (0.48) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL10066895 0.80 LMNA (0.44) LMNAALDH1A1EHMT2EHMT1APOBEC3G
SCHEMBL10035712 0.80 LMNA (0.44) LMNAALDH1A1EHMT2EHMT1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180155656-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-06-07 US disclosed
US-20180127590-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-10 US disclosed
US-20180119063-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180118946-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180118949-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180118948-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180119062-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180119061-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180118942-A1 REACTIVE LEUCO COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180119064-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
WO-2006099169-A2 NOVEL LIPOSOME COMPOSITIONS MEBIOPHARM CO., LTD. (JP) 2006-09-21 WO disclosed
EP-0516486-B1 Azetidinone derivatives useful in the preparation of carbapenem antibiotics SANKYO CO (JP) 2000-12-20 EP disclosed
CN-1038930-C Azetidinone derivatives useful in preparation of carbapenem antibiotics SANKYO CO (JP) 1998-07-01 CN disclosed
EP-0845459-A1 Azetidinone derivatives useful in the preparation of carbapenem antibiotics Sankyo Company Limited (JP) 1998-06-03 EP disclosed
US-5719275-A REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC SANKYO COMPANY, LIMITED (JP) 1998-02-17 US disclosed
US-5681951-A REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT SANKYO COMPANY, LIMITED (JP) 1997-10-28 US disclosed
US-5614624-A THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES SANKYO COMPANY, LIMITED (JP) 1997-03-25 US disclosed
US-5541317-A PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS SANKYO COMPANY, LIMITED (JP) 1996-07-30 US disclosed
CN-1068108-A Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics SANKYO CO (JP) 1993-01-20 CN disclosed
EP-0516486-A2 Azetidinone derivatives useful in the preparation of carbapenem antibiotics Sankyo Company Limited (JP) 1992-12-02 EP disclosed