Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158481 | 0.89 | APEX1 (0.36) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL3634989 | 0.88 | AKR1B1 (0.39) | CES2CES1 | |
| SCHEMBL3467327 | 0.86 | GPR84 (0.41) | — | |
| SCHEMBL9336189 | 0.86 | GPR84 (0.41) | — | |
| SCHEMBL4524385 | 0.85 | GRIK1 (0.33) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL2203074 | 0.85 | GRIK1 (0.35) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| Methacrylic Acid SCHEMBL7696921 | 0.84 | FNTA (0.37) | — | |
| SCHEMBL8746226 | 0.82 | ABCC4 (0.32) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL8139925 | 0.82 | CAMK2A (0.34) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| Methacrylic Acid SCHEMBL8161913 | 0.80 | GRIK1 (0.33) | GRIK1GRIK2GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6106605-A | ORGANOSILICON POLYMER | PPG INDUSTRIES OHIO, INC. (US) | 2000-08-22 | — | — | US | disclosed |
| US-5998123-A | MERCAPTOPYRAZOLONE DERIVATIVE COUPLERS | KONICA CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5693422-A | CONTAINING HYDROLYTIC POLYCONDENSATION PRODUCT OF A SILICON ALKOXIDE, AN ORGANOALKOXYSILANE AND A UV RAD ABSORBER OF A HYDROXYBENZOPHENONE OR HYDROXYBENZOTRIAZOLE | PPG INDUSTRIES, INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5385964-A | A radiation protective coating consisting of a reactive ultraviolet absorbing organic compound containing hydrophilic hydroxyl groups reacting with silanol groups to form silicon polymers; abrasion resistance | PPG INDUSTRIES, INC. (US) | 1995-01-31 | — | — | US | disclosed |