Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139925 | 0.89 | CAMK2A (0.34) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL8230756 | 0.85 | GRIK1 (0.33) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL8746226 | 0.82 | ABCC4 (0.32) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL158481 | 0.82 | APEX1 (0.36) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL2203074 | 0.81 | GRIK1 (0.35) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL3634989 | 0.81 | AKR1B1 (0.39) | — | |
| SCHEMBL9336189 | 0.80 | GPR84 (0.41) | — | |
| SCHEMBL8734090 | 0.80 | GRIK1 (0.33) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL3467327 | 0.80 | GPR84 (0.41) | — | |
| SCHEMBL9543435 | 0.78 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534262-B1 | Bimaterial intraocular implant and process for making the implant | IOLTECHNOLOGIE-PRODUCTION (FR) | 2009-05-19 | — | — | US | claimed |
| EP-1003446-B1 | IMPLANT FORMING BI-MATERIAL SINGLE-PIECE INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2004-09-01 | — | — | EP | claimed |
| EP-0647160-B1 | ION EXCHANGE RESIN | UNIV MONASH (AU) | 1998-09-02 | — | — | EP | claimed |