SCHEMBL8746226

SCHEMBL8746226

C=CCCC(=CC(C)C(=C)C(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
FAAH O00519 1/20 0.32
GRIK1 P39086 3/20 0.32
GRIA2 P42262 2/20 0.32
GRIA4 P48058 2/20 0.32
GRIK3 Q13003 2/20 0.32
GRIK5 Q16478 2/20 0.32
GRIK2 Q13002 2/20 0.32
GRIA1 P42261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4524385 0.82 GRIK1 (0.33) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL8230756 0.82 GRIK1 (0.33) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL158481 0.79 APEX1 (0.36) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL8139925 0.79 CAMK2A (0.34) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL2203074 0.78 GRIK1 (0.35) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL3634989 0.78 AKR1B1 (0.39)
SCHEMBL9336189 0.77 GPR84 (0.41) MAPTFAAH
SCHEMBL8734090 0.77 GRIK1 (0.33) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL3467327 0.77 GPR84 (0.41) MAPTFAAH
Acrylic Acid SCHEMBL9625364 0.76 ALOX15 (0.36) GRIK1GRIA2GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639590-B1 Process for preparing monodispersed poly (meth)acrylate particles ROEHM GMBH (DE) 1997-02-26 EP disclosed