Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823179 | 0.87 | XDH (0.35) | ALOX5 | |
| SCHEMBL1706160 | 0.82 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL823104 | 0.82 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL29823542 | 0.82 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL14069341 | 0.82 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL2343789 | 0.82 | KDM4E (0.41) | ALOX5 | |
| SCHEMBL18409845 | 0.79 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL823176 | 0.78 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL20714452 | 0.76 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL29823181 | 0.71 | KDM4E (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275721-A1 | METHOD FOR THE PURIFICATION OF SUBSTITUTED CYCLOPENT-2-EN-1-ONE CONGENERS AND SUBSTITUTED 1,3-CYCLOPENTADIONE CONGENERS FROM A COMPLEX MIXTURE USING COUNTERCURRENT SEPARATION | METAPROTEOMICS, LLC (US) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275721-A1 | METHOD FOR THE PURIFICATION OF SUBSTITUTED CYCLOPENT-2-EN-1-ONE CONGENERS AND SUBSTITUTED 1,3-CYCLOPENTADIONE CONGENERS FROM A COMPLEX MIXTURE USING COUNTERCURRENT SEPARATION | CYCS, CYP1B1, PDE1C | ALOX5 1912/4885ACHE 987/4885SOAT2 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.