Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218784 | 0.82 | SLC15A1 (0.45) | SLC15A1SLC7A5PTGS1DPP4FAP | |
| SCHEMBL997986 | 0.81 | SLC15A1 (0.66) | SLC15A1SLC7A5ALDH1A1PTGS1SMN1; SMN2 | |
| SCHEMBL995791 | 0.81 | SLC15A1 (0.66) | SLC15A1SLC7A5ALDH1A1PTGS1SMN1; SMN2 | |
| SCHEMBL996112 | 0.81 | SLC15A1 (0.66) | SLC15A1SLC7A5ALDH1A1PTGS1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4981923 | 0.80 | SLC15A1 (0.64) | SLC15A1SLC7A5ALDH1A1PTGS1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1758457 | 0.80 | SLC15A1 (0.64) | SLC15A1SLC7A5ALDH1A1PTGS1SMN1; SMN2 | |
| SCHEMBL244718 | 0.79 | SLC7A5 (0.69) | SLC7A5CYP3A4HIF1AALDH1A1ALOX15 | |
| SCHEMBL14559931 | 0.79 | SLC7A5 (0.48) | SLC7A5PTGS1DPP4MEN1KMT2A | |
| SCHEMBL44832 | 0.79 | SLC7A5 (0.69) | SLC7A5CYP3A4HIF1AALDH1A1ALOX15 | |
| SCHEMBL14355742 | 0.79 | SLC7A5 (0.48) | SLC7A5PTGS1DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011116-A2 | AZA-PEPTIDE PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |