SCHEMBL995791

SCHEMBL995791

N[C@@H](Cc1ccccc1)C(=O)CCl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 2/20 0.66
ALPI P09923 1/20 0.66
PKM P14618 1/20 0.66
PTGS1 P23219 1/20 0.66
XIAP P98170 1/20 0.66
SLC7A5 Q01650 1/20 0.66
LTA4H P09960 1/20 0.62
SLC1A3 P43003 2/20 0.51
SLC1A2 P43004 2/20 0.51
SLC1A1 P43005 2/20 0.51
HDAC8 Q9BY41 2/20 0.50
ANPEP P15144 2/20 0.49
RNPEP Q9H4A4 1/20 0.49
DNPEP Q9ULA0 1/20 0.49
CYP1A2 P05177 1/20 0.48
EPHX1 P07099 1/20 0.48
CTSC P53634 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
NCOA1 Q15788 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996112 1.00 SLC15A1 (0.66) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL997986 1.00 SLC15A1 (0.66) SLC15A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL4981923 0.98 SLC15A1 (0.64) SLC15A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL1758457 0.98 SLC15A1 (0.64) SLC15A1ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL6160157 0.84 LTA4H (0.61) LTA4HLAP3
SCHEMBL5060967 0.82 ALPI (0.68) SLC15A1ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28138410 0.82 SLC7A5 (0.88) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL12323250 0.82 SLC7A5 (0.68) SLC15A1ALPIPKMPTGS1XIAP
SCHEMBL28110902 0.82 ALPI (0.68) SLC15A1ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL430395 0.81 SLC7A5 (0.79) SLC15A1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1708740-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF DIGESTIVE PATHOLOGIES Rytek (FR) 2006-10-11 EP claimed
WO-2005077406-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF DIGESTIVE PATHOLOGIES RYTEK (FR) 2005-08-25 WO claimed
US-12030928-B2 Anti-influenza B virus neuraminidase antibodies and uses thereof ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2024-07-09 US disclosed
US-20240091337-A1 INFLUENZA B VIRUS MUTANTS AND USES THEREFOR FLUGEN, INC. (US) 2024-03-21 US disclosed
CN-117511844-A Non-invasive method for generating human nasopharyngeal three-and two-dimensional organoids 免疫与感染研究中心有限公司 2024-02-06 CN disclosed
EP-4267610-A1 COMPOSITION OF PIG POLYCLONAL ANTIBODY FOR ITS USE TO TREAT AND/OR PREVENT ANTIBODY-DEPENDENT MACROPHAGE PRO-INFLAMMATORY CYTOKINE RELEASE IN A PASSIVE ANTI-INFECTIOUS IMMUNOTHERAPY Xenothera (FR) 2023-11-01 EP disclosed
EP-4244378-A1 METHOD FOR DETECTING NUCLEIC ACIDS IN A BIOLOGICAL SAMPLE Innovative Diagnostics (FR) 2023-09-20 EP disclosed
EP-4205754-A1 ANTIVIRAL PLANT EXTRACT COMPOSITION AND METHOD FOR PREPARING SUCH COMPOSITION Cariel, Léon (FR) 2023-07-05 EP disclosed
EP-4205753-A1 ANTIVIRAL PLANT EXTRACT COMPOSITION AND METHOD FOR PREPARING SUCH COMPOSITION Cariel, Léon (FR) 2023-07-05 EP disclosed
US-11529409-B2 Influenza B virus mutants and uses therefor FLUGEN, INC. (US) 2022-12-20 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
EP-0159156-A1 Hydroxy substituted ureido amino and imino acids E.R. Squibb & Sons, Inc. (US) 1985-10-23 EP disclosed
EP-0154904-A1 Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines E.R. Squibb & Sons, Inc. (US) 1985-09-18 EP disclosed
US-4535176-A HYPOTENSIVE AGENTS, ANALGESICS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1985-08-13 US disclosed
EP-0142335-A2 Lactam containing compounds E.R. Squibb & Sons, Inc. (US) 1985-05-22 EP disclosed
US-4514391-A HYPOTENSIVE AGENTS; ANALGESICS E. R. SQUIBB & SONS, INC. (US) 1985-04-30 US disclosed
US-4512988-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-04-23 US disclosed
EP-0132304-A2 Hydroxy substituted peptide compounds E.R. Squibb & Sons, Inc. (US) 1985-01-30 EP disclosed
US-4474778-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1984-10-02 US disclosed
US-4470973-A HYPOTENSIVE AGENTS, ANALGESICS E. R. SQUIBB & SONS, INC. (US) 1984-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240091337-A1 INFLUENZA B VIRUS MUTANTS AND USES THEREFOR HAVCR2, CMBL, CD81 SLC15A1 3525/4885ALPI 3557/4885PKM 4752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.