Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | GNG2 | P59768 | 1/20 | 0.52 |
| ▸ | GNB1 | P62873 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814986 | 1.00 | MAPT (0.52) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL16281973 | 0.92 | GNG2 (0.61) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL31063767 | 0.88 | FTO (0.73) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL31110329 | 0.85 | FTO (0.65) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL31063709 | 0.81 | DHFR (0.46) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL2879470 | 0.81 | MEN1 (0.49) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29486478 | 0.81 | MEN1 (0.49) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL77954 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL30004394 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29474194 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2AFTOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971621-A1 | CASSETTE FOR TONOMETRIC CALIBRATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998037800-A1 | CASSETTE FOR TONOMETRIC CALIBRATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |