Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.47 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | TXN | P10599 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182506 | 0.91 | MLKL (0.43) | CHEK2MLKLALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3395279 | 0.87 | CHEK2 (0.50) | CHEK2MLKLALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8233161 | 0.83 | SLC2A1 (0.44) | ALDH1A1POLBCYP1A2CYP2C9MAPT | |
| SCHEMBL3395291 | 0.78 | MLKL (0.44) | CHEK2MLKLALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8235018 | 0.72 | ABL1 (0.39) | CHEK2MLKLALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6511830 | 0.71 | ALDH1A1 (0.67) | CHEK2ALDH1A1POLBSMN1; SMN2HPGD | |
| SCHEMBL3395254 | 0.70 | DRD4 (0.54) | ALDH1A1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL2464580 | 0.70 | ALDH1A1 (0.66) | ALDH1A1POLBSMN1; SMN2HPGDRAB9A | |
| SCHEMBL3396259 | 0.69 | TSHR (0.50) | ALDH1A1POLBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6367627 | 0.68 | POLB (0.55) | MLKLALDH1A1POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110868-A2 | HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS | ATIR HOLDING S.A. (LU) | 2007-10-04 | — | — | WO | disclosed |